Adaptation to Living With a BRCA1/2 Mutation

Plain-language summary

This study investigates how women carrying a BRCA1 or BRCA2 gene mutation and their partners adapt to this situation. It included women over 18 with a BRCA1/2 mutation and no personal cancer history, and their partners. It is an observational (non-phase) study and has been completed.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

N/A

Status

Completed

Sponsor

National Human Genome Research Institute (NHGRI)

Start date

5/2/2013

Estimated completion

2/20/2014

Countries

United States

Related genes

Locations

• Baltimore, United States

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

* INCLUSION AND EXCLUSION CRITERIA:

Participants will be women aged 18 or older who have a BRCA1/2 mutation and their (male or female) partners. Carriers must have no personal history of cancer, but partners will not be excluded based on cancer history. Participants will be asked to disclose their mutation status (BRCA1 or BRCA2), but no screening evaluation will be required. If only one member of a couple completes the survey, their data will be included in the individual level analysis, but excluded from the dyadic level analysis.