Biobank and Brain Health in Bordeaux.

Plain-language summary

This study creates a biobank to examine aging and brain health, using questionnaires, blood, saliva, urine and stool samples, neuroimaging and medical examinations. It enrolls people aged 55-80 who live in the Bordeaux area. This is a study without a phase and is currently recruiting participants.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

N/A

Status

Recruiting

Sponsor

University Hospital, Bordeaux

Intervention

Questionnaires, Fasting blood sampling., Saliva collection and nasal or nasopharyngeal swab, Urine and stool samples, Hair and a tonenail (or hand nail) sampling, Nasal microbiota, Measurements, Neuroimaging, Medical visit

Start date

3/22/2022

Estimated completion

3/22/2030

Countries

France

Related genes

Locations

• Bordeaux, France

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

For the main study:

1. live in Bordeaux metropolitan area,
2. be between 55 and 80 years old (included),
3. selected in terms of socioeconomic level, according to a sampling strategy by age groups and income categories representative of the general population between 55 and 80 years of age
4. be affiliated with the social security system,
5. agree to take a blood sample for the biobank.

For the MRI sub-study: be between 55 and 75 years old (included). Inclusion criteria for the immune response substudy: be 70 years of age or older or participate in the MRI study; agree to take a supplemental blood sample for this substudy.

Exclusion Criteria:

For the main study: persons under guardianship (or more generally under protection), unable to give consent to participate.

For the MRI sub-study: have a contraindication to MRI examination (pacemaker, a valve prosthesis or any other internal electrical/magnetic device; history of neurosurgery or aneurysm; claustrophobia; presence of metal fragments in the eyes, brain or spinal cord).