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This study looks at the effect of nonalcoholic red wine, compared with drinking water, on cognitive and locomotor (movement) abilities in people in early elderly age. Men and women aged 60 to 74 with sensory tolerance to red wine can take part. It is a study with no applicable phase and is currently recruiting participants.
The summary above is a plain-language rendering of the official record. The original English title is shown for reference.
Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.
Inclusion Criteria: 1\. Men or women between 60-74 years old; Sensory tolerance to red wine; Written informed consent provided before the initial screening visit. Exclusion Criteria: 1. Men or women \>75 years old, 2. Hypoglucaemiant treatment or type 1 and type 2 diabetes mellitus diagnosed 3. Anaemia (hemoglobin ≤13 g/dL in men and ≤12 g/dL in women) 4. Subjects diagnosed of intestinal disorders such as chron disease, colitis ulcerous, and irritable bowel syndrome 5. To present a clinical active chronic disease 6. To present severe sarcopenia 7. To present cognitive impairment (MMSE ≤ 24 or clinical diagnosis of mild cognitive impairment or dementia) 8. Dietary allergies to: Mediterranean foods (eg, nuts), sulphytes or nitrates 9. Use of antioxidants supplements 10. Regular consumers of red wine who do not agree to change the consumption of red wine with alcohol to nonalcholized wine during the intervention 11. Chronic alcoholism 12. Current or past participation in a clinical trial or consumption of a research product in the 30 days prior to inclusion in the study 13. Failure to follow the study guidelines. For participation in the muscle biopsy, additional exclusion criteria included: Use of prescription anti-platelet medication; Prescription anticoagulant use (or antiaggregant, or acenocoumarol; Conditions which would reduce healing; or known allergy to lidocaine.