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Lynch Syndrome

Prevalence: 1/440

oncologic

Official·OMIM:120435 Official·ORPHA144

Predisposition to colorectal and other cancers due to DNA mismatch repair gene mutations.

Associated Genes

MLH1MutL Homolog 1

Chromosome 3Autosomal Dominant

MSH2MutS Homolog 2

Chromosome 2Autosomal Dominant

MSH6MutS Homolog 6

Chromosome 2Autosomal Dominant

PMS2PMS1 Homolog 2

Chromosome 7Autosomal Dominant